Duniyar Data Direction
Hadin gwiwar ─eringerationation don gina wani yanki na yau da kullun da ke amsawa ga COVID-19 Pandemical
A farkon carenavirus ya soke a duk faɗin duniya ya haifar da ci gaba mai gudana a duniya Covid-19. Magana Saboda mayar da martani ga wannan duniyar ta COVID-19, COUO-Products Corp yana ba da gudummawa don tallafawa samar da rayuwarmu ta duniya.
A yanzu haka duniya ta fuskanta a halin yanzu sakamakon da ba a san shi ba game da cutar ƙwayar cutar Coronavirus cuta ta 2019 (COVID-19) Pandemic. Zuwa yau, babu wani ingantaccen magani da ake samu don lura da wannan cuta. Koyaya, an kirkiro gwaje-gwaje da yawa don gano CoviD-19. Waɗannan gwaje-gwajen sun dogara da hanyoyi masu ƙwayoyin cuta don gano takamaiman ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ko antabarry. Kamar yadda COVID-19 ya kai matsayin cutar pandemic, da farko sakamakon kamuwa da cutar corovirus na da muhimmanci a kimanin yaduwar kwayar cutar ta duniya ba tukuna ya wanzu tukuna ba tukuna. Dole ne mu san abin da gwaje-gwaje na iya amfani da shi don alwashin, ganewar asali, da lura da cututtukan CoviD-19, kuma menene iyakokinsu. Yana da mahimmanci yadda ake yin amfani da waɗannan kayan aikin kimiyya kuma don taimakawa gano da kuma sarrafa fitowar wannan hanzarin da sauri.
Dalilin gano ƙwayar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa ita ce ƙayyad da ko wanda ke da cakulan da yake da hankali ko kuma samar da ƙwayar cuta don jagorantar yanke shawara don jiyya na kulawa. Karatun da ya gabata ya nuna cewa kashi 70% na yanke shawara na Clinical sun dogara ne da sakamakon gwajin. Lokacin da ake amfani da hanyoyin gano abubuwa daban-daban, buƙatun na gano kayan da aka sake ganowa ma daban-daban.
Hoto na 1
Hoto1:Duauki yana nuna mahimman matakan gabaɗaya na gaba ɗaya yayin karatun lokaci na yau da kullun na cutar Covid-19. A X-Axis yana nuna yawan kwanakin kamuwa da cuta, kuma y-axis yana nuna nauyin ko bidiyo mai zagaya da sauri, da kuma maida hankali game da rigakafin a lokuta daban-daban. Antibodod yana nufin IGM da IGG abubuwan rigakafi. Ana amfani da gano RT-PCR da Antigen don gano kasancewar Coronavirus, wanda yake shaida madaidaiciya don farkon ganowa. A cikin mako guda na kamuwa da cuta ko bidiyo mai zagaya yanar gizo, ko gano Antigen. Bayan da labari Motar coronavirus na kimanin 7 kwanaki, rigakafin IGM a kan litattafan coronvirus sannu a hankali ya karu cikin jinin haƙuri, amma maida dumbarar kasancewarsa da sauri. Da bambanci, ƙwayoyin IGG da cutar sun bayyana daga baya, yawanci kusan kwanaki 14 bayan kamuwa da cutar. A hankali na iGG a hankali yana ƙaruwa, kuma yana ci gaba da dogon lokaci a cikin jini. Don haka, idan an gano IGM a cikin jinin mai haƙuri, wannan yana nufin cewa cutar ta kai kwayar cutar ta ko cutar, wacce ita ce alamar kamuwa da cuta. Lokacin da aka gano rigakafin IGG a cikin jinin mai haƙuri, wannan yana nufin cewa kamuwa da cutar ta hoto ta ɗan lokaci. Hakanan ana kiranta kamuwa da cuta ko kamuwa da cuta na baya. Ana ganin ana ganin shi a cikin marasa lafiya waɗanda suke cikin dawowar lokaci.
Da biomars na allo na coronavirus
Maganar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa shine ƙwayar cuta ta Rna, wacce ta ƙunshi sunadarai da acid ɗin nucleic. Kwayar cutar tana mamaye babban jiki (mutum) jiki, da sel ta hanyar da ke daɗaɗɗen wurin da ke da alaƙa da keɓantattun abubuwa kuma suna yin takamaiman abubuwan rigakafi. Saboda haka, acid ɗin nucleic acid da acidicens, da takamaiman abubuwan rigakafi da kuma takamaiman coronvirus za a iya amfani da su azaman takamaiman bionvirs Coronavirus. Don ganowar acijin acid, fasaha mafi yawanci ana amfani da ita, yayin da ake amfani da hanyoyin da aka saba amfani da su don gano ƙwayar cutar Coronavirus-takamaiman abubuwan rigakafi. A halin yanzu, akwai hanyoyin gwaji iri iri wanda zamu iya zaba don gwada cutar da ke covid-19 [1].
Ka'idojin Babban hanyoyin gwaji don Motoonavirus
Yawancin gwaje-gwajen bincike da yawa don COVID_19 suna zuwa yanzu, tare da ƙarin kayan gwajin da ke karɓar yarda a ƙarƙashin izinin amfani da gaggawa kowace rana. Kodayake sabon gwajin gwaji yana fitowa tare da sunaye da yawa daban-daban, duk gwajin covid_19 na rigakafi wanda ke gano takamaiman kayan kwalliya na hoto (IGM da Igg).
01. Ganowar acijin acidic
Raba trackit overcripip overcrifor-polymires sarkar dauki (RT-PCR), madauki-yada hanyoyin da ake amfani da shi (NSG), da kuma hanyar Searcharfin Kayayyakin Kayayyakin Coronavirus RNA. RT-PCR shine nau'in gwaji na farko don COVID-19, duka biyun da kungiyar Lafiya ta Duniya (WHO) da Amurka ta Amurka don Cibiyar Cututtukan cuta ta Cibiyar Cututtuka.
02.
Antibody shine furotin kariya wanda aka samar a jikin mutum don amsawa ga kamuwa da cutar. IGM shine farkon nau'in antibody yayin da igg wani nau'in antibody ne daga baya. Serum ko samfurin plasma yawanci ana bincika shi don kasancewar takamaiman IGM da IGG na antases na kimantawa na covid-19. Wadannan hanyoyin gano abubuwa masu ilimin-jini sun hada da katako mai kariya ta zinari mai kwakwalwa, latex ko mai kyalli micrunosorbenter. Enzea
03 -viyanci Antigen Gano
Antigen shine tsari game da kwayar cutar ta fuskar mutum wanda ke haifar da tsarin tsaro na rigakafi don samar da kwayar cuta don share kwayar cutar daga jini da kyallen takarda. A farkon Antigen da aka gabatar kan kwayar za'a iya kaiwa hari kuma ana gano ta hanyar amfani da Imunoassay. Kamar HNA VICH, antigens na hoto da kauna suma suna nan a cikin yanayin numfashi na mutane masu kamuwa da cutar kuma ana iya amfani dasu don haifar da cutar cututtukan ruwan sha na COVID-19. Sabili da haka, ana bada shawarar sau da yawa don tattara samfuran numfashi kamar siliki, Nasopharynengal swabs, mai zurfin jijiyoyin jiki don gwajin oriyanci.
Zabi hanyoyin gwaji don coronavirus
Zabi hanyar gwaji ya shafi abubuwa da yawa, ciki har da saitin asibiti, sarrafa ingancin tarin, kayan gwaje-gwaje, kayan gwaje-gwaje, kayan gwaje-gwaje. Gano na acid na nuclecis ko maganin acigens na hoto shine samar da shaidar kai tsaye ga ƙwayoyin cuta kuma ta tabbatar da gano cutar ƙwayar cutar ƙwayar cuta. Kodayake akwai hanyoyi da yawa don gano abubuwan ganowa, tunanin motsin zuciyarsu na litattafan litattafan litattafan ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta na sandar coronovirus ne ɓoyayyen ƙasa da na Rt-PCR Amplification. Gwajin rigakafi shine gano abubuwan rigakafi na rigakafi da aka samar a cikin jikin mutum, wanda yake kwance cikin lokaci kuma sau da yawa ba za a iya amfani dashi don gano cutar ƙwayar cuta ba. Saitin asibiti don aikace-aikacen ganowa na iya bambanta, kuma shafukan tarin tarin suna iya bambanta. Don gano ƙwayar lantarki ta atires da Antigens, samfuran yana buƙatar tattara samfuran numfashi inda yake, kamar Nasopharningal swabs, sputum, ko taguwar ruwa, ko browecharvealvare ruwa mai ruwa (baluf). Don ganowar ƙwayar cuta ta rigakafi, samfuran samfurin jini yana buƙatar tattara kuma ana bincika shi don kasancewar takamaiman takamaiman ƙwayar ƙwayar cuta (IGM / IGG). Koyaya, antibyda sakamakon gwajin nucleic na iya hadawa da juna. Misali, lokacin da gwajin gwajin shi ne - korau na acid-korau, IGM-korau amma na nuna rashin haƙuri, amma an gano shi daga kamuwa da cuta coronvirus. [2]
Abvantbuwan amfãni da rashin amfanin gwaje-gwajen coronvirus
A cikin ganewar asali da jiyya don maganin ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta ta ƙwaƙwalwa (tsarin gwaji na ƙasa), an yi amfani da gwajin ƙirar ƙasa na yau da kullun don ganewar asali Hakanan ana daukar gwajin kamuwa da cuta a matsayin ɗayan hanyoyin tabbatarwa don cutarwar.
Pathogenic da binciken serogical
(1) Ba'awar Pathogenic: Ana iya gano rubutun tsakar mahaifa a cikin Nasopharynownge swabs, sputum, ƙananan hanyoyin numfashi a jiki, jini, feces da sauran samfuran rt-pcrand / ko ngs. Zai yi daidai idan ana samun samfuran samfuran daga ƙananan numfashi na numfashi (sputum ko hakar Tract na iska). Ya kamata a gabatar da samfuran don gwaji da wuri-wuri bayan tarin.
(2) Binciken Tarurran: Musamman na ƙwayar cuta na NCP ya zama nazarin kusan kwanaki 3-5 bayan farawa; IGG ya kai wani takaddara akalla karuwa 4-ninka a lokacin confevescence idan aka kwatanta da m lokaci.
Koyaya, zaɓi na hanyoyin gwaji ya dogara da wuraren yanki, ka'idodin likita, da saitunan asibiti. A cikin USA, NIH wanda aka bayar da cutar Coronavirus Cutar Coronavirus ta 2019 (COVID-19) Manufar gaggawa ta Cutar Masana (Afrilu 21,2020) kuma FDA ta gaggawa ta Cutar Coronavirus Cutar cututtukan cuta (Afrilu 21,2020) da FDA na gaggawa (Afrilu 21) da FDA ), a cikin irin gwajin ƙwayar cuta na IGM / igg da aka zaɓa kawai azaman gwajin allo.
Hanyar gano Nucleic
Rt_pcr wani babban gwajin acidi ne mai mahimmanci wanda aka tsara don gano ko ko kuma sanannen coronavirus RNavirus RNA ke gabatarwa ko kuma wani samfurin. Sakamakon gwajin PCR na musamman yana nufin kasancewar ƙwayar cuta ta RNA a cikin samfurin don tabbatar da kamuwa da cutar CoVID-19. Sakamakon gwajin PCR mara kyau baya nufin rashin kamuwa da cutar ta saboda rashin ingancin yanayin rashin nasara ko kuma lokacin da ake mayar da shi a lokacin da aka dawo dashi, da sauransu. Kodayake RT-PCR gwaji ne mai matukar hankali, yana da halaka da yawa. Gwajin RT-PCR na iya zama aiki-m da cin abinci lokaci-lokaci, dogaro da babban ingancin samfurin. Wannan na iya zama ƙalubale ne domin adadin RNA vialy ba kawai ya bambanta a tsakanin marasa haƙuri ba, har ma da matattarar kamuwa da cuta ko kuma farkon bayyanar cututtuka. Gano sanannen littafin coronavirus yana buƙatar samfurori masu inganci waɗanda ke ɗauke da isasshen adadin incaract Virtial Stag.
Gwajin Tru-PCR na iya ba da mummunan sakamako mara kyau (ƙarya mara kyau) ga wasu marasa lafiya waɗanda ke da covid-19 na cutar. Kamar yadda muka sani, babban rukunin shafukan kamuwa da ƙwayar cuta Coronavirus suna a cikin huhu da ƙananan jijiyoyin jiki, kamar Alveoli da bronchi. Sabili da haka, samfurin sputum daga tari mai zurfi ko kayan molecoAlveolar ruwa mai zurfi (Balf) ya ɗauka yana da mafi girman hankali ga gano hoto ta hoto. Koyaya, a cikin aikin asibiti, ana tattara samfures daga saman numfashi na sama ta amfani da Nasopharynengal ko OropharyNeal Swabs. Tattara waɗannan samfuran ba kawai ba shi da daɗi ga marasa lafiya amma kuma yana buƙatar ma'aikata na musamman. Don yin samfuran ƙasa da ƙasa ko mafi sauƙi, a wasu halaye ana iya ba wa marassa lafiya daga mucosa ko harshe ya rushe kansu. Ba tare da isasshen RNA VIDED RNA ba, RT-QPCR na iya dawo da sakamakon gwajin karya. A cikin lardin Hubei, China, RT-PCR PCR PCR PCR a cikin ganowar farko an ruwaito kusan 30% -50%, tare da matsakaita na 40%. Babban adadin ƙarya - korau ne mafi kusantar lalacewa ta hanyar karamar samfuri.
Bugu da kari, gwajin rt-PCR yana buƙatar ma'aikata sosai don yin matakan haɓakar RNA da tsarin samar da Amplification. Hakanan yana buƙatar babban matakin kariya na biosafety, cibiyar bincike na musamman, da kuma kayan aikin PCR na ainihi. A china, gwajin rt-PCR don gano COVID-19 yana buƙatar aiwatar da shi a cikin dakunan gwaje-gwaje na Taros (BSL-2), tare da kariyar ma'aikata ta amfani da matakin farko. A karkashin waɗannan buƙatun, daga farkon watan Janairu zuwa farkon Fabrairu 2020, damar aikin binciken CDC na kasar Sin ya kasance kawai don gano wasu maganganun ɗari a rana. A yadda aka saba, wannan ba zai zama matsala ba lokacin da gwada sauran cututtuka cututtuka. Koyaya, lokacin da muke mu'amala da Pandemic na duniya kamar COVID-19 tare da yiwuwar miliyoyin mutane za a gwada, RT-19 PCR ta zama muhimmin al'amari saboda bukatun sa na kayan aikin sa na musamman. Waɗannan raunanawar na iya iyakance RT-PCR da za a yi amfani da su azaman kayan aikin ingantaccen kayan aiki, kuma na iya haifar da jinkiri a cikin rahoton sakamako.
Hanyar gano ƙwayoyin cuta
Tare da ci gaban cutar hanya, musamman a tsakiyar matakai da marigayi matakai, ƙimar gano ƙwayar cuta tana da girma sosai. Wani bincike a Asibitin Kudu na Kudu ya nuna cewa karancin ganowar rigakafi na iya isa sama da 90% a cikin mako na uku na kamuwa da cuta ta COVID-19. Hakanan, antibody shine samfurin abin rigakafi na rigakafi game da Maganar Coronavirus. Gwajin rigakafi yana ba da fa'idodi da yawa akan rt-PCR. Da fari dai, gwaje-gwaje na antiolody sauki da sauri. Za'a iya amfani da gwajin ƙwayoyin cuta na ƙwarewa don kulawa mai ma'ana don isar da sakamako a cikin mintina 15. Abu na biyu, manufa da aka gano ta hanyar gwajin baƙar magana shi ne antabod, wanda aka san shi ya zama mai tsayayye fiye da hoto ko bidiyo mai zagaya. A lokacin tattarawa, sufuri da gwaji, samfur don gwajin rigakafin suna da tsayayye fiye da samfuran don RT-PCR. Abu na uku, saboda an rarraba maganin rigakafi a cikin yaduwar jini, akwai ƙarancin ƙarancin samfurin idan aka kwatanta da gwajin nucleic acid. Samfurin samfurin da ake buƙata don gwajin rigakafi yana da ƙarami. Misali, jirgin ruwa na hoto 10 ya isa ya yi amfani da gwajin kwararar da ya kwarara.
Gabaɗaya, ana zaɓa gwajin riguna don kayan aiki na kayan aikin acidic don inganta yawan gano ƙwayar cutar Coronavirus a cikin darussan cutar. Lokacin da ake amfani da gwajin rigakafi tare da gwajin nucleic acid, yana iya ƙara daidaito daidai don maganin cutar COVID19 ta rage yiwuwar sakamako mai kyau da mara kyau. Jagorar aiki ta yanzu ba ta bada shawarar amfani da nau'ikan gwaji guda biyu daban ba azaman tsarin ganowa amma yakamata ayi amfani dashi azaman tsari. [2]
Hoto2:Fassarar da ta dace da yanayin aikin nucleic da sakamakon gwajin rigakafi don ganowar kamuwa da cutar Coronavirus
Hoto na 3:Liming Bio-Products Co., Ltd. - Ltd. - Motocon Coronavirus Igm / Igg®SARS-COV-2 IGM / IGG Daliban rigakafi
Hoto 4:Liming Bio-Products Co., Ltd. - Countsep®Littattafai (SARKIN-COV-2) Kit ɗin Kayan PCR-Kit (Gano don halittun halittun uku, hanyar bincike ta Claverescent).
SAURARA:Wannan mai matukar hankali, shirye-don amfani da Kit ɗin PCR yana samuwa a cikin tsarin lyophilized (daskararre-bushewa) don ajiya na dogon lokaci. Za a iya jigilar kayan kuma a adana shi a zazzabi a daki kuma an bartar tsawon shekara guda. Kowane bututu na premix ya ƙunshi dukkanin reagents da ake buƙata don samfurin PCR, gami da jujjuyawar ruwa da kuma dntps zai iya kawai sasantawa da samfuri da samfuri kuma kuyi kaya A kan kayan aikin PCR don gudanar da amplification.
A cikin martanin abin da Nassivirus na labari, liming bio-products Co., Ltd. ya yi aiki da sauri dakin bincike da na jama'a don taimakawa asibiti tare da gano cutar Clinical-19. Waɗannan abubuwan sun dace sosai don amfani don ƙwararrun allet a cikin ƙasashe da yankuna inda ake buɗe cutar Coronavires cikin hanzari da tabbaci ga cutar covid-19. Waɗannan abubuwan suna amfani da su ne kawai a ƙarƙashin izinin gaggawa na gaggawa (Peua). Gwajin yana iyakance ga dakunan gwaje-gwaje a ƙarƙashin ka'idodin hukumomin Kasa.
Hanyar gano gano
1. Ganowar hoto na Antigen Antigen an rarrabe shi a cikin nau'ikan gano kai tsaye azaman gano makaman acijin acijin. Wadannan hanyoyin ganowa kai tsaye suna neman shaidar cutar hannu ta cikin samfuri kuma ana iya amfani dasu don ingantaccen ganewar asali. Koyaya, ci gaban kayan tarihi na Antigen yana buƙatar haɓakar ƙwayoyin cuta na monoclonal tare da kusancin ƙwayoyin cuta da kuma ƙwarewar ƙwayoyin cuta Pathogenic. Yawancin lokaci yana ɗaukar watanni shida don zaɓar da haɓaka rigakafin monochlonal da ya dace don amfani da shirye-shiryen kit ɗin na Antigen.
2. A halin yanzu, masu karɓar don gano hanyoyin kai tsaye har yanzu suna ƙarƙashin bincike da ci gaba. Saboda haka, babu wani kit ɗin da aka gano Antigen da kuma samun kasuwa. Kodayake an ba da rahoton cewa a baya ya ba da izini cewa kamfani na asali a Shenzhen ya haɓaka kit ɗin ganowa da kuma daidaitawa a cikin Spain, abin dogaro da amincin asuwa, ba za'a iya ingantawa da daidaito ba saboda kasancewar batutuwa masu inganci. Zuwa yau, NMPA (tsohon FDA FDA) bai yarda da wani kit ɗin binciken Antigen don amfani da asibiti ba tukuna. A ƙarshe, an inganta hanyoyin da yawa na gano abubuwa. Kowace hanya tana da fa'idodinta da iyakoki. Sakamakon hanyoyi daban-daban ana iya amfani dashi don tabbatarwa da kuma cika.
3. Samar da ingancin gwajin COVID-19 ya dogara da ingantawa yayin bincike da ci gaba. Liming rio-samfurin Co., Ltd. Ana buƙatar kits na gwaji don sadar da masana'antu masu inganci da ingancin ingancin tabbatar da cewa sun samar da mafi girman matakan aiki da daidaito. Masana kimiyya a Liming CO., Ltd. suna da kwarewar shekaru ashirin a cikin ƙira, gwaji, da Inganta matakan bincike a cikin ƙididdigar ƙididdiga.
A lokacin Parvid-19, gwamnatin kasar Sin ta fafata da babbar babbar bukata ga kayan rigakafin cututtukan cututtukan cuta a cikin wuraren da kasa ta kasa. A ranar 5 ga Afrilu, a taron manema labarai na jihar hadin gwiwar kayayyakin kiwon lafiya da kuma karfafa tsari na kasuwa ", Jiang, na farko da sashen Kasuwancin Kasuwanci na Ma'aikatar Kasuwanci Na kasuwanci, ya ce, "Na gaba, zamu mai da hankali kanmu kan fannoni biyu, da farko, don hanzarta taimakon ƙarin kayan magani, da kuma sarrafa ingancin ingancin, tsari, da gudanar da samfuran. Zamuyi gudun gudar da kasar Sin ta ba da gudummawa ga cutar ta duniya kuma za ta gina al'umma da makomar mutane.
Hoto na 5:Liming Bio-Products Co., Ltd.'s Littattafan Coronavirus ya sami takardar shaidar rajista ta EU
Takaddun shaida
Houshshan
Hoto na 6. Liming Bio-Products Co., Ltd. An goyi bayan Wuhan Vultancan (Houshenshan) Asibitin Mountain-19 na Wuhan Red Cross. Asibitin Mountain Wuhan Valizan shine mafi shahara asibiti a China wanda ya ƙware a cikin lura da tsananin COVID - 19.
Kamar yadda farkon coronavirus ya ci gaba da yaduwa a duniya, Nanjing Liming Bio-Products Co., Ltd. yana hawa don tallafawa wannan barazanar da ba a bayyana ta duniya ba. Gwajin saurin gwaji na COVID-19 bangare ne mai mahimmanci na magance wannan barazanar. Muna ci gaba da bayar da gudummawa ta hanyar ingantacciyar hanya ta samar da ingantaccen tsarin bincike a cikin ma'aikatan tsaro na gaba don haka mutane zasu iya karbar sakamakon gwajin masu mahimmanci da suke buƙata. Yawan kayayyakin da ke haifar da kayayyaki na Bio-Products Co.
Dogon latsawa ~ scan kuma bi mu
Imel: sales@limingbio.com
Yanar Gizo: https://llingbio.com
Lokaci: Mayu-01-2020
